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This article gives an overview of the requirements and tasks for successfully operating Microsoft Defender for Endpoint in your organization. These tasks help your security operations center (SOC) effectively detect and respond to Microsoft Defender for Endpoint detected security threats.
This article also describes daily, weekly, monthly, and ad-hoc tasks your security team can perform for your organization.
Note
These are recommended steps; check them against your own policies and environment to make sure they are fit for purpose.
Prerequisites
The Microsoft Defender Endpoint should be set up to support your regular security operations process. Although not covered in this document, the following articles provide configuration and setup information:
Configure general Defender for Endpoint settings
- General
- Permissions
- Rules
- Device management
- Configure Microsoft Defender Security Center time zone settings
Set up Microsoft Defender XDR incident notifications
To get email notifications on defined Microsoft Defender XDR incidents, we recommend that you configure email notifications. For more information, see Incident notifications by email.
Connect to SIEM (Sentinel)
If you have existing security information and event management (SIEM) tools, you can integrate them with Microsoft Defender XDR. For more information, see Integrate your SIEM tools with Microsoft Defender XDR and Microsoft Defender XDR integration with Microsoft Sentinel.
Review data discovery configuration
Review the Microsoft Defender for Endpoint device discovery configuration to ensure it's configured as required. For more information, see Device discovery overview.
Daily activities
General
Review actions
In the action center, review the actions that have been taken in your environment, both automated and manual. This information helps you validate that automated investigation and response (AIR) is performing as expected and identify any manual actions that need to be reviewed. For more information, see Visit the Action center to see remediation actions.
Security operations team
Monitor the Microsoft Defender XDR Incidents queue
When Microsoft Defender for Endpoint identifies Indicators of compromise (IOCs) or Indicators of attack (IOAs) and generates an alert, the alert is included in an incident and displayed in the Incidents queue in the Microsoft Defender portal (https://security.microsoft.com).
Review these incidents to respond to any Microsoft Defender for Endpoint alerts and resolve once the incident has been remediated. For more information, see Incident notifications by email and View and organize the Microsoft Defender for Endpoint Incidents queue.
Manage false positive and false negative detections
Review the incident queue, identify false positive and false negative detections and submit them for review. This helps you effectively manage alerts in your environment and make your alerts more efficient. For more information, see Address false positives/negatives in Microsoft Defender for Endpoint.
Review threat analytics high-impact threats
Review threat analytics to identify any campaigns that are impacting your environment. The "High-impact threats" table lists the threats that have had the highest impact to the organization. This section ranks threats by the number of devices that have active alerts. For more information, see Track and respond to emerging threats through threat analytics.
Security administration team
Review health reports
Review health reports to identify any device health trends that need to be addressed. The device health reports cover Microsoft Defender for Endpoint AV signature, platform health, and EDR health. For more information, see Device health reports in Microsoft Defender for Endpoint.
Check Endpoint detection and response (EDR) sensor health
EDR health is maintaining the connection to the EDR service to make sure that Defender for Endpoint is receiving the required signals to alert and identify vulnerabilities.
Review unhealthy devices. For more information, see Device health, Sensor health & OS report.
Check Microsoft Defender Antivirus health
Viewing the status of Microsoft Defender Antivirus updates is critical for the best performance of Defender for Endpoint in your environment and up-to-date detections. The device health page shows current status for platform, intelligence, and engine version. For more information, see the Device health, Microsoft Defender Antivirus health report.
Weekly activities
General
Message Center
Microsoft Defender XDR uses the Microsoft 365 Message center to notify you of upcoming changes, such as new and changed features, planned maintenance, or other important announcements.
Review the Message center messages to understand any upcoming changes that impact your environment.
You can access this in the Microsoft 365 admin center under the Health tab. For more information, see How to check Microsoft 365 service health.
Security operations team
Review threat reporting
Review health reports to identify any device threat trends that need to be addressed. For more information, see Threat protection report.
Review threat analytics
Review threat analytics to identify any campaigns that affect your environment. For more information, see Track and respond to emerging threats through threat analytics.
Security administration team
Review threat and vulnerability (TVM) status
Review TVM to identify any new vulnerabilities and recommendations that require action. For more information, see Vulnerability management dashboard.
Review attack surface reduction reporting
Review ASR reports to identify any files that affect your environment. For more information, see Attack surface reduction (ASR) rules report.
Review web protection events
Review the web defense report to identify any IP addresses or URLs that are blocked. For more information, see Web protection.
Monthly activities
General
Review the following articles to understand recently released updates:
Security administration team
Review device excluded from policy
If any devices are excluded from Defender for Endpoint policies, review and determine whether the device still needs to be excluded from the policy.
Note
Review the troubleshooting mode for troubleshooting. For more information, see Get started with troubleshooting mode in Microsoft Defender for Endpoint.
Periodically
These tasks are seen as maintenance for your security posture and are critical for your ongoing protection. But as they may take time and effort, it's recommended that you set a standard schedule that you can maintain to perform these tasks.
Review exclusions
Review exclusions that have been set in your environment to confirm you haven't created a protection gap by excluding things that are no longer required to be excluded.
Review Defender policy configurations
Periodically review your Defender configuration settings to confirm that they're set as required.
Review automation levels
Review automation levels in automated investigation and remediation capabilities. For more information, see Automation levels in automated investigation and remediation.
Review custom detections
Periodically review whether the custom detections that have been created are still valid and effective. For more information, see Review custom detection.
Review alerts suppression
Periodically review any alert suppression rules that have been created to confirm they're still required and valid. For more information, see Review alerts suppression.
Troubleshooting
The following articles provide guidance to troubleshoot and fix errors that you may experience when setting up your Microsoft Defender for Endpoint service.